iS Clinical was founded in 2002 by biochemist Bryan Johns and entrepreneur Alec Call, who combined their expertise in science and business to create a skincare line that bridges the gap between botanical purity and pharmaceutical-grade efficacy. Operating under the Innovative Skincare umbrella, the brand is renowned for its commitment to developing clinically validated products that address a range of skin concerns, including aging, acne, and hyperpigmentation. Their formulations incorporate high-quality ingredients such as L-ascorbic acid (vitamin C), retinol, and plant-derived acids, aiming to deliver noticeable results in a short period. The brand's dedication to research and quality has garnered attention from prestigious publications like Harper's Bazaar and Allure, which have highlighted iS Clinical's innovative approach and effective formulations. Moreover, the brand has received praise from celebrities such as Jessica Alba, January Jones, and Rosie Huntington-Whiteley, who are known to use iS Clinical products as part of their skincare routines. This combination of scientific rigor, media recognition, and celebrity endorsement underscores iS Clinical's reputation as a trusted and effective skincare line.
Rosie Huntington-Whiteley Swears by iS Clinical Super Serum Advanced+
iS Clinical has carved a niche in the skincare industry with its scientifically formulated products that address key concerns such as anti-aging, acne, and hyperpigmentation. At the heart of their formulations is L-ascorbic acid, a potent form of vitamin C known for its antioxidant properties, which helps brighten the skin and reduce the appearance of dark spots by inhibiting melanin synthesis. The Pro-Heal Serum Advance+ combines this with vitamins E and A, olive leaf extract, and kojic acid, creating a synergistic blend that not only protects against environmental damage but also promotes skin healing and reduces inflammation. Retinol, a derivative of vitamin A present in their products, is clinically proven to minimize fine lines and wrinkles, improve uneven skin tone, and restore skin firmness by boosting collagen production. These ingredients work collectively to enhance skin texture and clarity, making iS Clinical products effective for a range of skin types, including sensitive and acne-prone skin. The brand's commitment to combining botanical extracts with advanced scientific research has garnered attention from both dermatologists and celebrities, solidifying its reputation as a leader in medical-grade skincare.
iS Clinical Pro Heal Serum Advanced+
iS Clinical Super Serum Advanced+
Given the extensive range of products offered by iS Clinical, it's essential to understand the specific purposes and clinical benefits of each formula. Two of the brand's most acclaimed serums—iS Clinical Super Serum Advanced and iS Clinical Pro-Heal Serum Advance+—are frequently compared, leading many to ask: what sets them apart? In this overview, we’ll take a closer look at the advanced ingredients and targeted functions of each serum to better understand their unique roles in skincare. This comparison will help determine which of these high-performance formulas is best suited to your individual skin needs and goals.
It is important to remember that consistency is the cornerstone of any effective skincare regimen. While it may be tempting to expect instant results, true improvements in skin health and appearance take time—typically around 6 to 12 weeks. This is because your skin operates on a natural renewal cycle, shedding dead cells and generating new ones over the course of about a month. Skincare products, especially those targeting concerns like acne, hyperpigmentation, and aging, need multiple skin cycles to fully take effect. Active ingredients such as retinoids, vitamin C, and peptides work gradually to improve texture, tone, and elasticity. Inconsistent use, switching products too frequently, or abandoning routines prematurely can interrupt progress and prevent you from achieving optimal results. By maintaining a daily routine—cleansing, treating, moisturizing, and protecting—you allow your skin the time it needs to respond, repair, and reveal visible transformation.
