Salmon sperm PDRN -short for polydeoxyribonucleotide -has rapidly become one of the most talked-about ingredients in regenerative aesthetics, but the fascination isn’t just hype-driven; it’s rooted in science. Originally used in medical settings for wound healing and tissue repair, PDRN is derived from purified DNA fragments (commonly sourced from salmon due to their biocompatibility with human DNA), and its primary function is to stimulate cellular regeneration. It works by activating adenosine A2A receptors, which helps promote tissue repair, improve microcirculation, reduce inflammation, and accelerate skin recovery. In skincare and injectable treatments, this translates into improved elasticity, enhanced hydration, strengthened skin barrier function, and a visibly smoother, more luminous complexion. Unlike traditional fillers that simply add volume, PDRN focuses on improving skin quality at a cellular level -encouraging fibroblast activity, supporting collagen synthesis, and helping compromised or aging skin repair itself more efficiently. This is why it has gained traction in Korean beauty clinics and high-end dermatology practices worldwide, especially for post-laser recovery, acne scarring, fine lines, and dull or damaged skin. But is it just a trend? While the “salmon sperm facial” headline certainly fuels viral curiosity, the underlying mechanism is supported by decades of regenerative medicine research. That said, topical PDRN products may not deliver the same dramatic results as injectable treatments, as penetration and concentration matter significantly. So, the popularity is partly marketing - the shock factor grabs attention -but the biological activity is legitimate. The real question isn’t whether PDRN works, but rather how it’s formulated, delivered, and used within a treatment protocol. In the right context, it’s less of a fleeting trend and more of a modern evolution in skin regeneration science - one that bridges cosmetic dermatology and true cellular repair.
Marini SkinSolutions’ Reboot PDRN Face Serum represents one of the most exciting evolutions in regenerative skincare by bringing clinically studied PDRN technology — the same polydeoxyribonucleotide fragments celebrated in advanced dermatology and aesthetic medicine-into a daily serum you can use at home. This next-generation formula harnesses highly purified salmon-derived PDRN, which has been shown in independent studies to promote fibroblast proliferation, enhance collagen synthesis, stimulate microcirculation and support tissue repair- key processes that help improve skin resilience, firmness, and overall texture over time.
What sets the Reboot serum apart is not just the inclusion of PDRN at a concentrated level, but the way it’s paired with complementary technologies, including peptides, hyaluronic acid, plant extracts, ceramides and antioxidant support- to provide multi-layer hydration, barrier restoration, soothing calm, and visible smoothing of fine lines and wrinkles.
Rather than a single-benefit product, it’s engineered to work across four core areas: enhanced recovery and repair, increased structural support, deep hydration and sustained barrier function, plus anti-inflammatory and defense support. This means that while it supports the natural “reboot” of skin at a cellular level-helping your complexion bounce back from aging, environmental stressors, or post-procedure sensitivity-it also strengthens and protects the skin you live in day-to-day.
Marini SkinSolutions-Marini Reboot
In an era where many buzzy ingredients come and go, Reboot PDRN stands out because it bridges regenerative science with everyday skincare use: it’s rooted in biological mechanisms that have been studied in medical literature yet formulated for regular application in a cosmetic routine.
A next-generation solution, featuring concentrated PDRN, for enhanced regeneration and rejuvenation in a single serum.
Marini Reboot
A Regenerative Reset
PDRN Powered Regeneration for Enhanced Skin Resilience and Longevity
Reboot Your Skin at Every Level
A next-generation solution, featuring concentrated PDRN, for enhanced regeneration and rejuvenation in a single serum. Support recovery, resilience, and long-term skin health for visibly smoother, younger looking skin with Marini Reboot™. An advanced PDRN solution optimized for daily topical skin care use
Core Regenerative Technology
PDRN: The Next Evolution In Professional Skin Care
Salmon-derived PDRN (polydeoxyribonucleotide)
PDRN is a new technology containing highly purified DNA fragments shown to support skin health and resilience, by providing the body with building blocks beneficial to enhanced recovery and repair.
Key Benefits:
Enhanced Recovery and Repair, Increased Skin Resilience, Visible Wrinkle Smoothing, Enhanced Radiance, Multi-Layer, Long-Lasting Hydration, Barrier Repair Support, Soothing & Calming of Inflamed Skin, Enhanced Protection & Support.
