The Biotech Revolution: Introducing Ourself Skincare
DermAvenue welcomes Ourself—a revolutionary brand created to bridge the gap between daily topical regimens and in-clinic aesthetic procedures. Ourself skincare delivers what was once only possible via injectables or professional treatments in a daily, non-invasive topical application.
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Ourself was built by biotech veterans who recognized a fundamental limitation in conventional topicals: the inability to deliver large, skin-transforming molecules deep into the skin without needles. Because of this, Ourself bridges the gap offering formulas that can realistically address issues like uneven pigmentation and delicate lip volume without injections.
The Science: Intides™ & Tiered-Release Vesicles™
At the heart of Ourself's patent portfolio lie two major technological pillars:
- Intides™ (Intelligent Peptides): Custom-engineered peptides designed to target specific cellular pathways, such as suppressing pigment formation in melanocytes or signaling fibroblast collagen synthesis.
- Tiered-Release Vesicles™ (TRV™ Delivery): A patented, multilayer vesicular delivery system designed to transport larger bioactive molecules deep past the stratum corneum barrier.
This proprietary subtopical delivery system is a major differentiator: whereas many skincare brands rely on simple liposomes that struggle to deliver large molecules effectively, Ourself’s TRV system has been clinically shown to penetrate into the deeper epidermal and dermal layers. It’s not just about what ingredients are used—it’s equally about how and where they are delivered.
Best Sellers & What Sets Them Apart
Ourself Lip Filler & Enhancing Regimen
The highly coveted ourself lip filler range taps into two major consumer desires: volume/definition and long-term nourishment. Powered by Subtopical Plumping Technology™, hyaluronic acid microspheres are infused directly into the lip tissue for instant and cumulative volume. Listed in “best of” plumper round-ups by InStyle, it offers a non-invasive alternative to clinical lip injections.
HA+ Replenishing Serum & Daily Renewal Cream
Shop Ourself HA+ Replenishing Serum
Among their face best-sellers, the HA+ Replenishing Serum is a powerful skin care serum clinically shown to improve firmness and smoothness (with Glamour calling it so effective it replaced injectables for one editor). Pair it with the ourself daily renewal cream—ranking high among dermatologist recommended moisturizers—where 89% of users felt their skin was softer and healthier after four weeks.
Related Clinical Skincare Guides
Ourself Mineral Sunscreen Broad Spectrum SPF 50
Shop Ourself Mineral Sunscreen
Fortified with Intides™ plus niacinamide to support tone and firmness while offering reef-friendly, broad-spectrum UV protection. It blends effortlessly onto the skin without leaving a chalky white cast.
The HA+ Replenishing Eye Serum
The HA+ Replenishing Eye Serum is a true standout, formulated with Subtopical delivery architecture that allows dual-weight hyaluronic acids, collagen-boosting Intides™, jasmine & hawthorn flower extracts, stabilized vitamin C, and niacinamide to penetrate deeper ocular zones.
Clinically, an 8-week study showed an 89% improvement in dark circles, an 82% improvement in fine lines, and an 88% reduction in redness. Featured in the ELLE 2023 Future of Beauty Awards, it is positioned to bridge the gap between daily eye creams and clinical aesthetic results.







